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Beta Thalassemia Treatment Cost in India

Beta Thalassemia Treatment in India
Beta-thalassemia is characterized by decreased beta-globin synthesis. It is an inherited blood disorder, which means that at least one of your parents is a carrier. When you have beta-thalassemia, your body produces less hemoglobin than usual. Hemoglobin is an iron protein found in red blood cells, which transport oxygen throughout the body. Regular blood transfusions are arranged by healthcare providers and physicians for beta-thalassemia treatment in India. Other treatments may include bone marrow transplants, iron-lowering medications, daily folic acid, and so on.

The estimated cost of beta-thalassemia treatment in India is very low. The best-specialized hematologist in India provides exceptional medical care to patients suffering from beta-thalassemia.

What is Beta Thalassemia?

Beta-thalassemia is a genetic blood disorder characterized by a lack of beta-globin chains in hemoglobin. Hemoglobin allows red blood cells to transport oxygen to the rest of your body’s cells and tissues.

To generate energy, the cells use oxygen from red blood cells. Low hemoglobin levels can result in a shortage of mature red blood cells and a lack of oxygen in the body. One of the two types of thalassemia is beta-thalassemia. Beta-thalassemia is classified into two primary subtypes based on the severity of its symptoms:

  • Thalassemia Major (called Cooley’s anemia): A severe form characterized by severe anemia as well as enlarged liver and spleen.
  • Thalassemia Intermedia- A milder form that causes less anemia and does not necessitate regular blood transfusions.

What are the Symptoms of Beta Thalassemia?

The severity of your beta-thalassemia will determine your symptoms. With beta-thalassemia minor, you may have no symptoms or only mild anemia symptoms. Beta-thalassemia intermedia, and especially beta-thalassemia major, can cause moderate to severe symptoms. Here are some of the symptoms of beta-thalassemia:

  • Fatigue
  • Dizziness
  • Headaches on a regular basis
  • Pale (yellowish) skin
  • Shortness of breath
  • Heart palpitations
  • Symptoms of jaundice
  • Dark or tea-colored urine
  • Slow growth or delayed development
  • Abdomen swelling
  • Weak or misshapen bones in the arms, legs, and face.
  • Infants that have moderate to severe beta-thalassemia may get infections on frequent basis.

Signs and symptoms of thalassemia intermedia can appear in early childhood or later in life. The severity of this disease can vary and depend on the nature of the mutation.

What are the Causes of Beta-Thalassemia?

Most cases of beta-thalassemia are caused by mutations in the HBB gene. A mutation in the alpha-globin chain causes alpha thalassemia, while mutations in the beta-globin chain cause beta-thalassemia, and mutations in the HBB gene eliminate or reduce beta chain production, causing hemoglobin damage.

A person becomes a carrier if they inherit one copy of a genetic mutation. This means they will be able to pass the gene on to their biological children. They will have mild symptoms, but in the majority of cases, they will have no symptoms at all.

A person who inherits two copies of the mutated gene may develop severe beta-thalassemia.

The disorder is frequently caused by the deletion of genetic material on the HBB gene, but many cases are hereditary and passed down through families.

How the Diagnosis of Beta Thalassemia is Done?

A blood sample from a vein is usually taken and analyzed by your doctor for the diagnosis of beta-thalassemia. Tests may include the following:

  • A complete blood count (CBC): The CBC test tells you about your blood cells and red blood cells. The test determines whether you have too few red blood cells and whether they are smaller, oddly shaped, or pale.
  • Reticulocyte count: Reticulocytes are also known as immature red blood cells. If your reticulocyte count is low, it means that your body is not producing enough red blood cells. This can also lead to serious health problems such as anemia and bone marrow and liver disorders.
  • Molecular genetic testing: Molecular genetic testing is typically used to detect changes in a single gene as well as large duplication or depletion, allowing the doctor to closely examine the hemoglobin and identify the mutation associated with beta-thalassemia.
  • Hemoglobin electrophoresis: The hemoglobin electrophoresis test measures different types of hemoglobin proteins, providing healthcare providers with a snapshot of the situation.

If there are any concerns that the fetus may carry the mutated gene, the doctor may perform chorionic villus sampling (CVS) or amniocentesis during pregnancy. A person with beta-thalassemia may require additional ongoing tests of their organs and organ systems.

Beta Thalassemia Treatment Cost in India

The average cost of beta-thalassemia treatment in India starts from USD 20000.

The cost may also vary depending on other factors such as the number of travelers, the country from which one is traveling, and the number of days spent in India for thalassemia treatment.

Procedure

How Beta Thalassemia is Treated? 

Because there are no cures for beta-thalassemia. The type of symptoms and severity of the disorder determines how beta-thalassemia is treated. Treatment options include:

  • Blood transfusions: With beta-thalassemia major, blood transfusions may be required as frequently as every two weeks. A patient will receive blood from a donor during this procedure.
  • Iron chelation therapy: Iron is an essential component of hemoglobin, allowing it to transport oxygen. Too much iron, on the other hand, can be harmful. Iron chelation therapy is used to prevent iron overload.
  • Folic acid supplements: Folic acid improves the body’s ability to produce red blood cells. If you have beta thalassemia minor, your doctor may advise you to take supplements. If your condition is severe, your doctor may recommend that you take folic acid in addition to receiving regular blood transfusions.
  • Luspatercept: Patients with severe thalassemia may be given Luspatercept injections every three weeks to help the body produce morered blood cells. Luspatercept frequently improves anemia in people with beta-thalassemia who are receiving blood transfusions.
  • Bone marrow and stem cell transplant: A donor’s bone marrow stem cells may be given to patients. Replacing bone marrow stem cells with healthy donor stem cells can help cure beta-thalassemia. Unfortunately, finding a compatible donor can be difficult, and this type of transplant is considered a high-risk procedure.

Know More – Paediatric Bone Marrow Transplant Cost in India

What are the Complications of Beta-Thalassemia?

A complication can vary depending on the type such as:

  • Thalassemia minima– mild and will cause no problems but that person will be the carrier of the disorder.
  • Thalassemia intermedia– causes problems based on the severity of the symptoms. Problems include weak bones, delayed growth, and enlarged spleens.
  • Beta thalassemia major– will cause you major problems which can result in early death.

 Suggestions 

Living with beta-thalassemia major or intermedia can be difficult for you or anyone because you may need to manage medical care as well as other thoughts and feelings that may arise. Many people with this disease can live normal lives if they are properly cared for and given the best treatment for the prevention, as there is no cure. To receive proper care, you must work together with your healthcare provider. Because beta-thalassemia can be passed down from parent to child, a person with beta-thalassemia should consult with their healthcare providers, who will provide you with the resources you will need.

How can Medsurge India Help? 

Medsurge India is a prestigious support system for patients looking for doctors, hospitals, and specialized treatments. We’ll find the most suitable medical options for you. Regarding your medical issues, our team will give you a list of certified, reputable, and trusted doctors and hospitals. Additionally, we offer a treatment strategy that fits your budget. Apart, we assist patients with obtaining travel authorizations, medical visas, and a multitude of other things.

The Most Important Frequently Asked Questions

Q: Is beta-thalassemia serious?

A: Beta-thalassemia can result in early death and will cause major problems. Complications like delayed growth, liver, heart problems and diabetes, etc can be included.

Q: What is the life expectancy of someone with beta-thalassemia?

A: Patients or a person with beta-thalassemia can have a normal life expectancy. A person can live to an average of 17 years or by the age of 30 years. The majority of death is caused due to cardiac complications or iron overload.

Q: Can thalassemia go away?

A: Based on the condition it can cause mild to server anemia and can be passed to their children. Note that there is no cure.

Q: How common is beta-thalassemia?

A: This disease is fairly common worldwide. There are thousands of infants with Beta-thalassemia that are born each year. 

Q: Does beta-thalassemia make you tired?
A: Beta-thalassemia produces either no or little hemoglobin. This makes a person very anemic i.e. tired, pale, and short of breath. 

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