Chronic Myelogenous Leukemia (CML) Treatment Cost in India
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The malignancy of the bone marrow, the spongy tissue found inside bones where blood cells are formed, is rare and is known as chronic myelogenous leukemia (CML). The amount of white blood cells in the blood rises as a result of CML. Though it can happen to anybody at any age, it mainly affects elderly individuals and happens very infrequently in children. Doctors in India assess the patient’s preferences and general health before recommending a course of treatment. Other considerations include the disease’s stage, potential side effects, and treatment choices. People with chronic myelogenous leukemia in India now have a significantly better prognosis because of medical advancements. After diagnosis, the majority of patients will have remission and live a long time.
Treatment for chronic myelogenous leukemia in India is much lesser as compared to other developed countries like the US, America, Russia, etc. Together with the skill of an oncologist, hematologists, and the state-of-the-art medical equipment used at the top Indian hospitals may be partially credited for the success. In addition to these advantages, India is well known for its low costs without lowering clinical standards.
Chronic myelogenous leukemia (CML) is a kind of cancer that develops in the bone marrow’s blood-forming cells. Chronic refers to the fact that this malignancy often advances more slowly than acute myeloid leukemia (AML). The term “myelogenous” describes the kind of cells that are harmed by this kind of cancer. The illness is also known as chronic granulocytic leukemia or chronic myeloid leukemia
A particular alteration in the bone marrow stem cell is the cause of CML’s onset. Particularly, BCR-ABL, an aberrant gene, is present in CML cancer cells. This gene produces a protein that fuels the uncontrolled growth of cancer cells. Therefore, the bone marrow creates an excessive amount of granulocytes (a type of white blood cell). Blasts, or immature white blood cells, build up over time. Your bone marrow finds it challenging to create typical red blood cells, white blood cells, and platelets as a result.
There are many phases of chronic myelogenous leukemia. Each one demonstrates how aggressive the cancer is. The three main stages of chronic myelogenous leukemia are as follows:
Chronic myelogenous leukemia treatment cost in India starts from INR 11,66,000 (14,000 USD). India offers healthcare at significantly lower costs as compared to other countries. Furthermore, the quality of the medical services and treatment provided there is on par with that of the best hospitals in the world. Even without taking travel, lodging, and food expenses into account, the price of treatment is much affordable than other countries.
Factors That Can Affect Chronic Myelogenous Leukemia Treatment Cost in India
The following indications or symptoms may be present in people with CML. Or, a medical disease other than leukemia might be to blame for a symptom. But because CML often advances slowly, symptoms might not show up for a while. Typically, the symptoms start off modest and gradually develop worse. Additionally, many CML patients have no symptoms at all. Blood tests performed for another cause are most frequently used to detect CML. When they appear, warning indicators may include:
Most frequently, CML is discovered during a regular blood count. Your healthcare practitioner will schedule additional tests to confirm your diagnosis if they have any reason to believe you may have CML. These tests might consist of:
The samples of blood or bone marrow tissue is taken may be subjected to one of the following tests:
Patients with chronic myelogenous leukemia can choose from a variety of treatments. Clinical trials are being conducted to evaluate various therapies, some of which are conventional. Here are some of the most widely used to treatments for Chronic Myelogenous Treatment in India:
Chemotherapy is a form of cancer treatment that employs medications to kill cancer cells or prevent them from proliferating in order to limit the development of cancer cells. Chemotherapy enters the circulation whether administered orally or by injection into a vein or muscle, where it can reach cancer cells throughout the body (systemic chemotherapy).
Immunotherapy is a form of cancer treatment that activates the patient's immune system. Utilizing compounds created by the body or in a laboratory, the body's natural defenses against cancer are strengthened, directed, or repaired. Cancer patients may get biological therapy.
A form of therapy called targeted therapy identifies and kills particular cancer cells using medicines or other chemicals. Compared to chemotherapy or radiation therapy, targeted therapies often have a lower impact on healthy cells.
To eradicate cancer cells, high dosages of chemotherapy are administered. Cancer therapy also destroys healthy cells, such as blood-forming cells. A therapy to replenish the blood-forming cells is a stem cell transplant. The patient's or a donor's bone marrow is harvested for its stem cells (immature blood cells), which are then frozen and kept in storage. The patient receives an injection of thawed-out stored stem cells following the conclusion of treatment. These stem cells are reinfused and develop into (and replenish) the body's blood cells.
A splenectomy can be required if leukemia extends to the spleen even though surgery cannot be used to treat CML directly. Spleen swelling brought on by leukemia may cause it to push excessively against neighboring organs. It’s crucial to highlight, however, that surgery has no function in treating chronic myelogenous leukemia.
Hospitals that specialize in treating Chronic Myelogenous Leukemia are well known for their high standards of treatment and hospitality. Some of India's leading oncologists, hematologists, and subject-matter authorities are housed in these hospitals. A foreign patient may find it difficult to choose a reputable facility for treatment. It is a significant decision that must be taken while bearing several considerations in mind, such as:
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A1: The primary medication used to treat CML is a drug called imatinib. It is often administered quickly after a cancer diagnosis in order to decrease the disease's course and keep it from progressing to an advanced stage. Reduced formation of aberrant white blood cells is how imatinib works.
A2: The first line of treatment for CML is tyrosine kinase inhibitors (TKIs). In May 2001, imatinib became the first oral TKI to be authorized for the treatment of CML. Second- and third-generation TKIs, including dasatinib and nilotinib, were subsequently authorized for use as first-line therapies.
A3: The frequency of your treatment visits will depend on the location of your illness and the type of cancer you have. It may take around 5 months for chemotherapy.
A: The illness eventually spreads to different body parts. Being classified as chronic often means that this particular kind of leukemia spreads and develops slowly. However, CML has the potential to transform from a slowly developing form of leukemia into an acute version with fast growth that can affect virtually every organ in the body.
A5: Patients with CLL have a wide range of prognoses at the time of diagnosis. Some people experience a quick demise due to CLL complications, within 2-3 years after diagnosis. The majority of patients have a lifespan of 5 to 10 years, with a relatively benign first course that is followed by a fatal, progressive, and resistant phase lasting 1-2 years.
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