Lutetium-177 Treatment Cost in India

Lutetium Treatment in india

Lutetium-177 PSMA Therapy, also known as Prostate-Specific Membrane Antigen Therapy, is becoming an increasingly popular therapy for men with advanced prostate cancer who have metastasis or have tumors that are resistant to other treatments.

Lu-PSMA therapy in India is a treatment for patients with advanced-stage prostate cancer or those who have not responded to traditional methods of therapy. The therapy is a highly accurate treatment that can help to protect healthy surrounding tissue while delivering high dosage radiation to cancer cells.

The Cost of Lutetium-177 PSMA Therapy in India is quite affordable as compared to other developed countries. In India, the average price starts from USD .It is determined by the hospital room rates (Room Category – Multi-room, Twine Sharing, Single Room, and so on) as well as the doctor’s fee. The success rate of Lutetium-177 PSMA Therapy in India is extensively high.

What is PSMA?

Many prostate cancers, particularly those that have progressed or grown resistant to hormonal treatments, display a specific receptor termed Prostate Specific Membrane Antigen (PSMA) on their cell surface. When prostate cancer metastasizes, or spreads to other parts of the body, the PSMA receptor is also expressed at the metastasis sites. PSMA is an excellent target for prostate cancer radionuclide imaging and therapy for various reasons:

  • It is found in nearly all Prostate Cancers at all stages of the disease.
  • It is increased in patients with hormone-refractory or metastatic illness.
  • It is an integral cell membrane protein that is not discharged into the bloodstream.
  • After Antibody Binding, PSMA is internalized (Receptor-mediated Endocytosis).

What is Nuclear Medicine Therapy?

Nuclear medicine Therapy in India is a technique for diagnosing and treating various types of disorders that involve just a small amount of radioactive material. Nuclear medicine is generally used to treat patients with thyroid tumors or hyperactive thyroid glands, neuroendocrine tumors, prostate cancers, lymphomas, and liver tumors.

A small amount of radioactive material or radioisotope, known as Radiopharmaceutical, is used in this targeted therapeutic strategy to kill cancer cells. To deposit fatal radiation into the tumor, the radioactive chemical is conjugated with a tumor-targeting agent. It can be taken as a drink, an injection, or a capsule.

Nuclear Medicine Therapy in India is provided by top prominent hospitals, including Fortis Memorial Research Institute. The Nuclear Medicine section at FMRI is a specialized unit prepared to perform several types of radioisotope therapy. It is the country’s referral institution for Iodine therapy for thyroid cancer and a pioneer in Lutetium therapies for neuroendocrine tumors. It is India’s first Lutetium PSMA therapy center and has treated many patients with this therapy. FMRI’s Nuclear Medicine department is now the only one in India to provide myeloablative MIBG therapy for high-risk neuroblastomas in children, as well as the first to provide Targeted alpha therapy for neuroendocrine tumors, prostate cancer, and certain brain tumors.

Who is a Right Candidate for Lutetium-177 PSMA Therapy in the Treatment of Prostate Cancer in India?

You may be eligible if you have prostate cancer that has gone beyond the prostate and has progressed despite prior treatments (including hormonal therapies and at least one chemotherapy). To ensure that you qualify for Treatment with Lutetium-177 PSMA in India, you must first have a PSMA PET scan, which is accessible in Best Nuclear Medicine Therapy Hospital in India.


What is the Cost of Lutetium-177 PSMA Therapy in India

Lutetium-177 PSMA Therapy Costs in India start from 9800 USD per course. A course on average, and a patient receiving lutetium-177 PSMA therapy will typically receive three or four courses. Lu-177 therapies, such as PSMA and PRRT therapy, are typically recommended to fourth-stage cancer patients after all other therapeutic options have been exhausted. These medicines improve patients’ health and standard of life, resulting in significantly higher survival rates.

However, the overall Nuclear Medicine Therapy Cost in India starts from USD. The Treatment cost plan may differ from person to person and type of hospital chosen by the patient.

How Does Lutetium-177 PSMA Therapy Work

PSMA is a protein that is generated on the membrane of prostate cells and is believed to have a variety of biological activities. Although the prostatic epithelium produces very small amounts of PSMA normally, malignant prostate tumors produce extremely large amounts (sometimes 1,000 times more than a normal prostate cell). PSMA will be identified if prostate cancer has spread to other parts of the body. 

Lutetium-177 is a radioactive material that emits beta radiation, which is a type of damaging radiation. Lutetium-177 binds to a short peptide that attaches to the PSMA receptor found on the surface of cancer cells. The Lutetium-177 PSMA complex, once attached to the prostate cancer cell, emits destructive radiation, causing the cancer cell to die. Because the released beta particle has a very low penetration, the surrounding normal cells are undisturbed.

Lutetium-177 Treatment for prostate cancer


Before the Procedure:

  • Patients are not required to do fasting or make any other preparations before undergoing diagnostic imaging or therapy infusion. 
  • The nuclear medicine team will provide all necessary supporting care to the patient.

During the Procedure:

  • On an average week later, the team will follow up the PET scan with the lutetium-177 PSMA, another injectable radioactive element that specifically targets the cancer that was detected on the PET scan.  
  • To administer the medication, an IV is inserted into the patient’s arm; the injection takes only a few minutes. Patients are observed for one to two hours before sending them to home.
  • A doctor would normally check on patients every three weeks to screen for side effects, which may include extracting blood.
  •  If you’re doing well and reacting well, we’ll continue with the therapy.  The treatments are once every six weeks for a total of six treatments.

After the Procedure:

  • Most patients go through three to four therapy cycles at 8-12 week intervals. Depending on the response and interim evaluations, the number of cycles and interim time may differ between individuals. 
  • The average dose of Lu PSMA Therapy in India provided per treatment is in the range of 5.5-11GBq, and the doses are based on pre-treatment dosimetry (Dosimetry is the measurement, computation, and assessment of the ionizing radiation dose received by the human body).
  • View your PDF report on what to do in the two to three days following therapy to ensure the patient’s and family’s safety. 

Helpful – Best Nuclear Medicine Hospitals in India

What are the Benefits of Lutetium-177 PSMA Therapy in India?

This therapy improves the quantity and quality of life for patients who would otherwise have few treatment alternatives. Most patients who are suitable for this therapy are already suffering from cancer-related symptoms that are affecting their quality of life. As the majority of patients respond to the medication, their symptoms improve and their quality of life improves. It’s also well tolerated, thus from a risk/benefit and quality of life standpoint, this medication is highly effective.

How can Medsurge India Help

Medsurge India is a prestigious support system for patients looking for doctors, hospitals, and specialized treatments. We’ll find the most suitable medical options for you. Regarding your medical issues, our team will give you a list of certified, reputable, and trusted doctors and hospitals. Additionally, we offer a treatment strategy that fits your budget. Apart, we assist patients with obtaining travel authorizations, medical visas, and a multitude of other things.

The Most Important Frequently Asked Questions

Q: What are the disadvantages of lutetium-177?

A: Although Lu-177 PSMA therapy is considered safe because the dose of Lutetium-177 radiation is carefully checked for each patient prior to treatment, some adverse effects might be predicted, including an increased risk of bleeding, Nausea,  Dry Mouth.

Q: Who is a candidate for lutetium-177 PSMA therapy in the treatment of prostate cancer?

A: You may be eligible if you have prostate cancer that has gone beyond the prostate and has progressed despite prior treatments (including hormonal therapies and at least one chemotherapy).

Q: How is lutetium recovered?

A: The mineral monazite, like many other lanthanides, is the primary source of lutetium. It is extracted by reducing anhydrous fluoride with calcium metal, which is a challenging process.

Q: Is lutetium safe?

A: Ingestion of lutetium is mildly hazardous, however its insoluble salts are non-toxic. Lutetium, like other rare-earth metals, has a low toxicity rating, although it and its derivatives should be handled with caution.

Q: Does lutetium-177 work?

A: Lutetium-177 therapy is only used on men who have prostate cancer and have exhausted all other treatment options. It has been shown to be a successful medication for treating metastatic prostate cancer or prostate cancer after other treatments have failed.

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