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Non Hodgkin’s Lymphoma Treatment
Non-Hodgkin’s Lymphoma is a type of cancer that begins in the lymph nodes and lymphatic tissue of organs such as the intestines, stomach, and skin. It may also involve the blood or bone marrow at times. In humans, hundreds of lymph nodes are found throughout the body and are classified as secondary lymphoid organs. NHL is divided into several subtypes, each of which grows at a different rate. Chemotherapy is the primary Treatment for Non-Hodgkin’s Lymphoma in India because it involves the use of drugs or medicine to kill cancer cells. Other treatments, such as image therapy and radiation therapy, are also employed. To suppress your bone marrow and immune system, a or stem cell transplant may be performed. 

The Cost of Non-Hodgkin’s Lymphoma Treatment in India is lower than in other countries. Patients seeking treatment for NHL in Indian hospitals are provided with affordable healthcare packages as well as high-quality machinery or equipment, as well as the assurance of excellent treatment quality with top-class doctors.

What is a Non-Hodgkin’s Lymphoma?

Non-Hodgkin Lymphoma is a type of blood cancer that begins in the lymphatic system. They are inherited genetic disorders. These conditions are not inherited. Instead, they occur when genes within specific cells mutate or change. The affected cells in this case are B-lymphocytes (B cells) or T-lymphocytes (T cells), which are part of your immune system.

Non-Hodgkin’s Lymphoma (NHL) Is not a single disorder, but rather a group of blood cancers that all develop from lymphocytes. These cells can form in one or more locations throughout the body.Non-Hodgkins Lymphoma is classified into two types:

  • B-Lymphocytes (B cells): B cells help protect the body against germs like bacteria or viruses by making proteins called antibodies.
  • T-Lymphocytes (T cells): You can find many types of T cells in the body. Where some T cells destroy germs or abnormal cells in the body. While other T cells help in boosting or slowing the activity of other immune system cells.

What are the Signs and Symptoms of Non-Hodgkin’s Lymphoma?

Signs and symptoms of Non-Hodgkin’s Lymphoma are also associated with a number of other, less serious diseases.

According to research, the human body contains approximately 600 lymph nodes. A painless swelling in one or more lymph nodes is a common early sign of Non-Hodgkins Lymphoma.

The majority of NHL patients have one or more enlarged lymph nodes in the neck, armpit, or groin. A swollen node may appear near the ears, elbow, or in the throat near the tonsils on occasion. It can sometimes begin in places other than the lymph nodes, such as the bone, lung, gastrointestinal tract, or skin. 

Common symptoms of NHL include:

  • Painless swelling in one or more lymph nodes 
  • Unexplained fever
  • Sweating during the night
  • Persistent fatigue
  • Appetite loss
  • Unknown cause of weight loss
  • Coughing or chest pain
  • Pain in the abdomen
  • Trouble Breathing
  • Sensations of bloating or fullness
  • Skin itching
  • Enlargement of the liver or spleen
  • Skin rashes or lumps

In some cases, patients may not exhibit any symptoms, and the disease may be discovered during a routine medical examination or while the patient is being treated for another condition.

What Exactly Causes Non-Hodgkin’s Lymphoma?

Non-Hodgkin’s Lymphoma is caused by a mutation in the DNA of a type of white blood cell called lymphocytes, although the exact reason why this happens isn’t known. Non-Hodgkin’s Lymphoma develops when your body produces an abnormally high number of leukocytes, or white blood cells. Healthcare providers are unaware of all of the possible causes. White blood cell growth mutations play a role. (These are acquired genetic mutations, which means you develop them rather than being born with them.) They also know that people with certain infections or immune system problems are more likely to develop non-Hodgkin lymphoma.

How is Non-Hodgkin’s Lymphoma Diagnosed?

Every disease necessitates an accurate diagnosis because it is one of the most important aspects of a person’s treatment. Furthermore, a precise diagnosis can assist the physician or doctor in:

  • Calculate the disease progression rate
  • Determine the best course of action

Several tests will be used by doctors and physicians to diagnose Non-Hodgkin Lymphoma.  The following are some of the diagnostic procedures:

  • Physical exams: These can be used to determine the size and condition of your lymph nodes. Physical examinations will also aid in the detection of an enlarged liver or spleen.
  • Blood tests and urine tests: They are performed to rule out infection and other diseases, as lymph nodes can swell at any time when your body is fighting an infection.
  • Imaging tests: Such as the following, which aid doctors in the detection of tumors, stages of cancer, and types of cancer:
  1. X-ray
  2. CT scan
  3. MRI
  4. Positron emission tomography (PET) scan
  5. Ultrasound
  6. Bone scan

In other tests, such as a biopsy, a small portion of the lymph node is removed for testing. Because it can aid in the identification of NHL. A bone marrow biopsy can also help your doctor or physician determine whether or not the disease has spread.

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What are the Treatment Options for Non-Hodgkins Lymphoma Patients?

Non-Hodgkins Lymphoma Treatment in India can vary depending on age, type of NHL, and stage of NHL.

Doctors may or will monitor whether NHL is slow-growing or fast-growing and if it’s causing any symptoms. Treatment can wait until the disease progresses. However, if your non-Hodgkin’s lymphoma is aggressive and causes signs and symptoms, your physician may recommend treatment options like:

  • Chemotherapy: It’s a drug that kills cancer cells in the body. They are administered orally or by injection. These medications can be used alone, in combination with other chemotherapy medications, or in combination with other therapies. Cytophosphamide (Cytoxan), oxaliplatin (Eloxatin), pentostatin (Nipent), vincristine (Marqibo), and bleomycin are among the medications used.  Chemotherapy is also used as part of a stem cell transplant for patients with Non-Hodgkin’s Lymphoma. A high dose of chemotherapy drugs may help your body prepare for the transplant.
  • Radiation Therapy: Cancer cells are killed using high-powered energy beams. Your doctor will have you lie down on a table while a large machine moves around you, directing energy beams to specific points on your body. Radiation therapy alone can treat you if you have a slow-growing lymphoma in one or two spots. Radiation is more commonly used after chemotherapy to kill any remaining lymphoma cells in your body.
  • Targeted Drug Therapy: By blocking the abnormalities in the body, this treatment targets specific abnormalities present within cancer cells. Cancer cells are killed by targeted drug treatments. Targeted drugs can be used alone or in combination with chemotherapy to treat non-Hodgkin’s lymphoma. This combination can be used as an initial treatment as well as a second treatment if your lymphoma reappears.
  • Engineering immune cells to fight lymphoma: Chimeric Antigen Receptor (CAR)-T cell therapy modifies the body’s germ-fighting T cells to fight the tumour before reinfusing them into the body. Certain types of B-cell non-Hodgkin’s lymphoma that have not responded to other treatments may be candidates for CAR-T cell therapy.
  • Bone Marrow Transplant: A bone marrow transplant is also known as a stem cell transplant. High doses of chemotherapy and radiation are used to suppress your bone marrow and immune system. Healthy bone marrow from a donor or your own body can be infused into your bloodstream, where it will travel to your bones and rebuild your bone marrow. If other treatments have failed to cure Non-Hodgkin’s Lymphoma a bone marrow transplant may be an option.
  • Immunotherapy: Fighting cancer with your immune system. Sometimes cancer cells produce proteins that help them hide from the immune system. This prevents them from being detected by your body’s immune system and attacking it. Immunotherapy is used to counteract the disease by interfering with the process. The antigen-targeting antibodies are obinutuzumab (Gazyva), ofatumumab (Arzerra), and ibritumomab tiuxetan (Zevalin).

The cost of NHL treatment in India is determined by several factors, such as:

  • The severity of the condition
  • The location and accreditations of the hospital were chosen.
  • Surgical experience
  • Hospital stay duration 
  • Room type
  • If any additional procedures are required

What are the Complication of Non-Hodgkin’s Lymphoma Treatment?

Even if they are cured, some patients with non-Hodgkin lymphoma have long-term problems. These are some instances of complications:

  • Weak immune system- Patients with a weakened immune system are said to be more susceptible to infections and have a higher risk of developing serious complications as a result of the infections. Symptoms include a high temperature, headache, muscle aches, and so on. If you experience any of the symptoms, please notify your doctor.
  • Vaccination- As live vaccines contain a weakened form of the organism being vaccinated against, ensure that all of your vaccinations are up to date. BCG vaccine is an example (against tuberculosis).
  • Infertility- Infertility may result from treatments such as radiation therapy or chemotherapy.


Patients with Non-Hodgkin’s Lymphoma can live normal lives if they follow the doctor’s treatment recommendations based on the severity of the disease or diagnosis. However, people’s health and treatment complications can vary greatly. To receive the care you require, you must work with your healthcare provider and your doctor. Don’t be afraid, and keep in mind that you are not alone. Your healthcare provider can supply you with the tools and resources you’ll need to care for yourself.

How can Medsurge India Help? 

Medsurge India is a prestigious support system for patients looking for doctors, hospitals, and specialized treatments. We’ll find the most suitable medical options for you. Regarding your medical issues, our team will give you a list of certified, reputable, and trusted doctors and hospitals. Additionally, we offer a treatment strategy that fits your budget. Apart, we assist patients with obtaining travel authorizations, medical visas, and a multitude of other things.

The Most Important Frequently Asked Questions

Q: Is Non-Hodgkins Lymphoma a dangerous cancer?

A: It can be either indolent (slow to grow) or aggressive (fast-growing). NHL can spread and grow at various rates.

Q: Is non-Hodgkins Lymphoma curable?

A: A low-grade tumor does not require immediate medical treatment, but it can be difficult to completely cure, whereas a high-grade tumor requires immediate medical treatment, responds much better to treatment, and is frequently cured.

Q: What is the overall survival rate for Non-Hodgkin’s Lymphoma?

A: It has been determined that 73% of patients survived after being diagnosed.

Q: Where does lymphoma begin to spread?

A: The liver, bone marrow, and lungs are the primary organs where it begins to spread.

Q: What triggers Lymphoma?

A: A: People who have immune system diseases or who take drugs that suppress their immune system are more likely to develop lymphoma.

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