Cost of Dendritic Cell Therapy
What is Dendritic Cell Therapy?
Dendritic cell therapy is an advanced immunotherapy technique that uses the body’s immune system to identify and kill outgrown cancerous cells. In this therapy, our body’s immune system is modified to a level that it can target and kill different types of cancerous cells without causing harm to normal cells.
It is an advanced and promising approach to the treatment and prevention of cancer.
Dendritic cell therapy cost in India is starts from roughly 1500 USD per dose and the records say that the treatment became beneficial for many patients.
Patients who have completed therapy with success have reported positive outcomes and favor this method of cancer treatment over others.
Basic Facts of the Dendritic Cells
Dendritic cells are an essential part of our immune system. The cells are part of our innate (natural) immune system that helps in the killing of unwanted foreign pathogens when they enter our body.
For a long time, the therapy has been widely used in combating different types of cancer diseases like melanoma, prostate, breast cancer, and many more.
In scientific terms, dendritic cells are known as antigen-presenting cells. The term antigen refers to any foreign substance that enters our body but is not required.
Why Choose Dendritic Cell Therapy?
The patients suffering from different types of cancers are eligible for the treatment. It is a natural treatment that patients can take along with or separately from other cancer treatments. Usually, in countries like India, the therapy is given along with other cancer therapies.
Over the decades, doctors use traditional approaches like chemotherapy and radiotherapy for cancer treatment. But these traditional procedures have their consequences and side effects. However, dendritic cell therapy in India is an efficient technique for treating cancer due to the following reasons:
- Minimally-Invasive Therapy
Dendritic cell therapy is minimally-invasive. Being minimally invasive means that the treatment does not require a complex surgical procedure, chemicals, and radiation.
- Pain-Free Process
It is a pain-free treatment that does not require complex surgical procedures but requires a little incision.
- Natural Treatment
The therapy uses the natural healing system of your body.
- No Side Effects
Since, the treatment is based on a natural healing system, not on chemicals or radiation, there are no possible side effects.
- Immunity Booster
The laboratory-mediated dendritic cell is twice stronger than our normal dendritic cells against the cancerous tumor.
There is a 100% assurance that these cells boost our immune system for specific identification, recognition, and killing of the cancerous cells.
- Reduced Risk of Recurrence
As it directly attacks the cancerous cells, there are no or very few chances of having cancer twice.
- Appropriate For Treating Tumor
The therapy is most appropriate for tumor-based cancers. Why you may ask? It is because it directly targets and deals with the tumor cells and not just their symptoms.
What is the Role of Dendritic Cells in Cancer Therapy?
There is a specific role of dendritic cells in cancer therapy. First of all, the dendritic cells are also known as antigen-presenting cells as they present antigens (foreign substances) in front of fighter or killer cells to eliminate foreign antigens.
Based on this natural theory, dendritic cell therapy in India is the ultimate technique for treating cancer. You can consider lab-mediated dendritic cells therapy as the vaccine for cancer. The scientists customize the vaccines according to the specific cancer patient requirements. Though they make it according to the specific cancer type, the dendritic cells directly target the cancerous cells instead of eliminating the cause of cancer.
The experts take your blood sample, extract dendritic cells and culture them in the laboratory for modification. When the cell modifies, the doctor injects the cells into the patient’s body where the cells are capable of targeting cancerous cells. The dendritic cells present the targeted cells to the immune system for killing them.
Dendritic Cell Therapy Can Treat the following Types of Cancers:
- Breast cancer
- Prostate cancer
- Uterine cancer
- Intestinal cancer
- Ovarian cancer
- Kidney cancer
- Pancreatic cancer
- Colorectal cancer
- Liver cancer
- Renal cancer
- Gastric cancer
- Colon cancer
- Esophageal Cancer
- Acute lymphoblastic leukemia
- Acute myeloid leukemia
- Cervical cancer
- Bladder cancer
- Endometrial cancer
- Stomach cancer
- Hodgkin lymphoma
- Small lung cancer
- Salivary gland cancer
What is the Success Rate of Dendritic Cell Therapy?
- On a normal daily basis, our body produces around 6000 cancerous cells but only some of us develop serious cancer due to the weaker immune system.
- According to the research, there is a 60% chance of cancer treatment. The average response rate of the vaccine is 10-15%.
- The dendritic cell vaccination activates the more specific immune response against cancerous cells. But a number of things affect the success rate.
- The survival rate differs according to the type of cancer. For colorectal carcinoma, the survival rate for dendritic cell therapy alone is 58.1 %. However, when the therapy is combined with other methods like chemotherapy, the chances of survival rate increases up to 76%.
What are the Post-Treatment Consequences?
You might wonder if there are any side effects associated with dendritic cell therapy. The doctors recommend approx. 4-6 shots of vaccine within a week. During that phase, the doctors or other hospital staff take special care of patients ensuring detoxification, a clean environment, nutrition, and the patient’s psychological state.
After receiving the vaccine, some of the patients may develop mild side effects.
The list of consequences that can occur:
- Muscle ache
- Joint pain
- Nausea or vomiting
- Trouble breathing
- Low or high blood pressure
- Allergic reaction
- Tingling reaction
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Dendritic Cell Therapy Cost
From the year 2010, the government gave approval to the dendritic cell vaccine for the treatment of prostate cancer. Currently, the vaccine treats other types of cancer too. The cost of the treatment depends on the location of the center and cancer type Since there are multiple clinical phases, the procedure cost starts from 3000 US$ per dose.
The therapy cost starts from 1500 US$ per dose. The cost depends on the location and the type of treatment that a particular hospital or clinic applies.
In European countries, the average cell-based therapy costs about 5101.20 US$ for a single vaccine. However, the cost range may vary in case of additional treatment.
The average cost in Dubai is 93,000 USD for a one-year treatment having 6 doses.
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- Extraction of Blood sample
The doctors take blood samples of the patients who suffer from any of the above-mentioned cancer. Since the blood consists of a mixture of blood cells, the sample undergoes the process of centrifugation inside the laboratory. Based on the density, the different cells are separated into layers.
- Extraction of Monocytes
The laboratory expert extracts the monocyte cells from a mixture of cells. Monocytes are the premature versions of dendritic cells. The experts grow monocytes cells inside the culture media and provide them with specific growth factors so that the cells become useful therapeutic agents.
- Exposure to Antigen
Dendritic cells are exposed to particular tumor antigens in the lab by specialists. The cells are then “primed.”
- Injection of Dendritic Cells
The blood sample is extracted from the cancer patients and sent to the lab for dendritic cell extraction and modification. After being for 1 whole week inside the laboratory, the modified form of mature dendritic cells becomes target-specific and ready to perform a therapeutic function. The doctors inject back the dendritic cells into the patient’s body.
- Presentation of Antigen or Cancerous Cell
Inside the body, the dendritic cells recognize the foreign antigen or cancerous cells and then present it to the cytotoxic T-cells. The T -cells are the crucial part of our immune system responsible for killing unwanted cells.
The Most Important Frequently Asked Questions
Frequently Asked Questions
Some of the concerning questions that people usually ask regarding the therapy are as follows:
Q: How long does the therapy procedure take?
A: The dendritic cell therapy on average takes 17 days for the complete treatment.
Q: Where can I get the dendritic cell therapy?
A: The approved treatments are efficiently performed in Germany, Spain, the Czech Republic, China, and Israel. However, other countries like India, Japan, the UK, etc., also have facilities regarding the therapy.
Q: How quickly can we see the results?
A: The cancer vaccine using dendritic cells as the therapeutic agent takes 3 months to prepare. After taking the vaccine, the results are visible between 6 to 9 months.
Q: Are there any side effects?
A: Patients can show mild effects such as dizziness, flu-like symptoms, fever, headaches, etc.
Q: Am I eligible for dendritic cell therapy?
A: It is beneficial for the treatment of various types of cancer including tumor, carcinoma, or metastasis.
Q: What can I do for the fastest recovery?
A: If you have undergone dendritic cell therapy, then follow the advice as doctors suggest you do. Visit respective clinics once a week or month to observe the therapeutic effects.