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Cost of Dendritic Cell Therapy

What is Dendritic Cell Therapy?

Dendritic cell therapy is an advanced immunotherapy technique that uses the body’s immune system to identify and kill outgrown cancerous cells. In this therapy, our body’s immune system is modified to a level that it can target and kill different types of cancerous cells without causing harm to normal cells. 

It is an advanced and promising approach for the treatment and prevention of cancer

Dendritic cell therapy cost in India is roughly 96000 USD and the records say that the treatment became beneficial for many patients. 

The patients who have already surpassed the treatment have shown good results and also recommend it to other people over other cancer treatment approaches.

Know The Basics of Dendritic Cells

Dendritic cells are a crucial part of our immune system. The cells are part of our innate (natural) immune system that helps in the killing of unwanted foreign pathogens when they enter our body. 

For a long time, the therapy has been widely used in combating different types of cancer diseases like melanoma, prostate, breast cancer, etc. 

In scientific terms, dendritic cells are known as antigen-presenting cells. The term antigen refers to any foreign substance that enters our body but is not required.

The German scientist Paul Langerhans first discovered the dendritic cells in the 19th century. Later, Ralph M. Steinman and Zanvil A. Coin coined the term dendritic due to its or ‘tree-like’ or ‘branch-like’ appearance. 

Why Choose Dendritic Cell Therapy?

The patients suffering from different types of cancers are eligible for the treatment. It is a natural treatment that patients can take along with or separately from other cancer treatments. Usually, in countries like India, the therapy is given along with other cancer therapies.

Over the decades, doctors use traditional approaches like chemotherapy and radiotherapy for cancer treatment. But these traditional procedures have their consequences and side effects. However, dendritic cell therapy is an efficient technique in treating cancer due to the following reasons:

Minimally-Invasive

Dendritic cell therapy is minimally-invasive.  Being minimally invasive means that the treatment does not require a complex surgical procedure, chemicals, and radiation.

Pain-Free

It is a pain-free treatment that does not require complex surgical procedures but requires a little incision.

Natural Treatment

The therapy uses the natural healing system of our body.

No Side Effects

Since, the treatment is based on a natural healing system, not chemicals or radiation, there are negligible chances of side effects. 

Immunity Booster

The laboratory-mediated dendritic cell is twice stronger than our normal dendritic cells against the cancerous tumour. 

There is a 100% assurance that the cells boost our immune system for specific identification, recognition, and killing of the cancerous cells.

Reduced Risk of Recurrence

As it directly attacks the cancerous cells, there are no or very few chances of having cancer twice.

Appropriate For Treating Tumour

The therapy is most appropriate for tumour-based cancers. Why you may ask? It is because it directly targets and deals with the tumour cells and not just their symptoms.

Dendritic Cells in Cancer Therapy 

There is a specific role of dendritic cells in cancer therapy. First things first, the dendritic cells are also known as antigen-presenting cells as they present antigen (foreign substances) in front of fighter or killer cells to kill such antigen. 

Based on this natural theory, dendritic cell therapy is the ultimate technique for treating cancer. You can consider lab-mediated dendritic cells therapy as the vaccine for cancer. The scientists customize the vaccines according to the specific cancer patient. Though they make it according to the specific cancer type, the dendritic cells directly target the cancerous cells instead of eliminating the cause for cancer. 

They take our blood, extract dendritic cells and culture them in the laboratory for modification. When the cell modifies, the doctor injects the cells into the patient’s body where the cells are capable of targeting cancerous cells. The dendritic cells present the targeted cells to the immune system for killing them.

Dendritic Cell Therapy Can Treat Different Types of Cancers:

  • Sarcoma
  • Melanoma
  • Breast cancer
  • Prostate cancer
  • Uterine cancer
  • Intestinal cancer
  • Ovarian cancer 
  • Kidney cancer
  • Glioblastoma
  • Pancreatic cancer
  • Colorectal cancer
  • Liver cancer
  • Renal cancer 
  • Mesothelioma
  • Gastric cancer 
  • Colon cancer
  • Esophageal Cancer
  • Acute lymphoblastic leukaemia
  • Acute myeloid leukaemia
  • Cervical cancer
  • Bladder cancer
  • Endometrial cancer
  • Retinoblastoma
  • Stomach cancer
  • Hodgkin lymphoma
  • Small lung cancer
  • Salivary gland cancer
  • Skin-cancer

Dendritic Cell Therapy Success Rate 

On a normal daily basis, our body produces around 6000 cancerous cells but only some of us develop serious cancer due to the weaker immune system.

According to the research, there is a 60% chance of cancer treatment. The average response rate of the vaccine is 10-15%. 

The dendritic cell vaccination activates the more specific immune response against cancerous cells. However, the success rate depends upon several factors. 

 The survival rate differs according to the type of cancer. For colorectal carcinoma, the survival rate for dendritic cell therapy alone is 58.1 %. However, when the therapy is combined with other methods like chemotherapy, the chances of survival rate increase up to 76%.

Frontiers | Dendritic Cell Cancer Therapy: Vaccinating the Right Patient at the Right Time | Immunology (frontiersin.org)

 Post-Treatment Consequences

You might wonder if there are any side effects associated with dendritic cell therapy. The doctors recommend approx. 4-6 shots of vaccine within a week. During that phase, the doctors or other hospital staff take special care of patients ensuring detoxification, clean environment, nutrition, the patient’s psychological state.

After receiving the vaccine, some of the patients may develop mild side effects. 

The List of Consequences That Can Occur:

  • Fever
  • Dizziness
  • Chills
  • Weakness
  • Muscle ache
  • Joint pain
  • Nausea or vomiting
  • Headache
  • Trouble breathing
  • Fatigue
  • Low or high blood pressure
  • Allergic reaction
  • Tingling reaction
  • Sensitivity
Dendritic Cell Therapy Cost

From the year 2010, the government gave approval to the dendritic cell vaccine for the treatment of prostate cancer. Currently the vaccine treats other types of cancer too. The cost of the treatment depends on location of the center and  cancer type Since there are multiple clinical phases, the procedure cost starts from 1000 US$.

Cancer therapy by dendritic cells (prices, hospitals, reviews, procedures)) (medica-tour.com)

The therapy cost ranges from  18150.14 US$ to 26889.09 US$. The cost depends on location and type of treatment that particular hospital or clinic applies. 

How Dendritic Cell Therapy Helps In Cancer Treatment? | Medinirvan

 

In European countries the average cell-based therapy costs near about 5101.20 US$   for a single vaccine. However, cost range may vary in case of additional treatment.

Dendritic Cell therapy & Supporting Strategies – Cancer Treatments – from Research to Application (cancertreatmentsresearch.com)

The average cost in Dubai is 93,000 USD for a one-year treatment having 6 doses.

Procedure
Procedure for Dendritic Cell Therapy
Extraction of Blood sample

The doctors take blood samples of the patients who suffer from any above-mentioned cancer and. Since the blood consists of a mixture of blood cells, the sample undergoes the process of centrifugation inside the laboratory.

Based on the density, the different cells are separated into layers.

Extraction of Monocytes

The laboratory expert extracts the monocyte cells from a mixture of cells. Monocytes are the premature versions of dendritic cells. The experts grow monocytes cells inside the culture media and provide them with specific growth factors so that the cells become useful therapeutic agents. 

Exposure to Antigen

Inside the lab, the experts provide exposure of dendritic cells to specific cancer antigens. The cells then become primed.

Injection of Dendritic Cells

The blood sample is extracted from the cancer patients and sent to the lab for dendritic cell extraction and modification. After being for 1 whole week inside the laboratory, the modified form of mature dendritic cells become target-specific and ready to perform a therapeutic function. 

The doctors inject back the dendritic cells into the patient’s body.

Presentation of Antigen or Cancerous Cell

Inside the body, the dendritic cells recognize the foreign antigen or cancerous cells and then present it to the cytotoxic T-cells. The T -cells are the crucial part of our immune system responsible for killing unwanted cells.

 

The Most Important Frequently Asked Questions

Frequently Asked Questions

Some of the concerning questions that people usually ask regarding the therapy are as follows:

Q: How long does the therapy procedure take?

A: The dendritic cell therapy on average takes 17 days for the complete treatment.

Q: Where can I get the dendritic cell therapy?

A: The approved treatments are efficiently performed in Germany, Spain, the Czech Republic, China, and Israel. However, other countries like India, Japan, the UK, etc., also have facilities regarding the therapy.

Q: How quickly can we see the results?

A: The cancer vaccine using dendritic cells as the therapeutic agent takes 3 months to prepare. After taking the vaccine, the results are visible in between 6 to 9 months.

Q: Are there any side effects?

 A: Patients can show mild effects such as dizziness, flu-like symptoms, fever, headaches, etc.

Q: Am I eligible for dendritic cell therapy?

A: It is beneficial for the treatment of various types of cancer including tumor, carcinoma, or metastasis.

Q: What can I do for the fastest recovery?

A: If you have undergone dendritic cell therapy, then follow the advice as doctors suggest you do. Visit respective clinics once a week or month to observe the therapeutic effects.

 

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Medsurge India is one of the pioneers and the most reputable company in the field of medical tourism in India. India offers World Class Medical Facilities, comparable with any of the Western and European countries. India has state of the art Hospitals and the finest medical experts. With the most excellent infrastructure, the best possible Medical facilities, accompanied with the most competitive prices, you can get the treatment done in India at the lowest charges. The Availability of Ayurveda and Naturopathy in the purest form makes India the most sought after health destination.

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