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Hemophilia Treatment Cost in India

Hemophilia is a clotting condition that causes the blood to clot slowly. Following an injury, surgery, or having a tooth extracted, people with this syndrome experience persistent bleeding or dribbling. Continuous bleeding occurs in severe cases of hemophilia after minimal trauma or even in the absence of injury (spontaneous bleeding). Bleeding into the joints, muscles, brain, or other internal organs can have serious consequences. Milder varieties of hemophilia do not always cause spontaneous bleeding, and symptoms may not appear until abnormal bleeding occurs after surgery or a catastrophic accident. 

What is Hemophilia?

It is natural for humans to get sick or injured over the course of their lives. When we are harmed, our body’s clotting mechanism fights to stop the bleeding. However, in certain cases, blood does not clot and bleeding cannot be regulated by the body naturally due to a gene malfunction. Hemophilia is a bleeding disorder that is extremely rare. This gene is then handed down through the generations and reason to that  Hemophilia is considered as an inherited condition.

Hemophiliacs, or people who have hemophilia, are born without the clotting factor, which is handed down in families. This clotting factor is a protein found in the blood that helps to keep bleeding under control. Both males and females are affected by hemophilia. Hemophiliac men pass the mutated gene to their daughters but not to their sons. Sons with the gene, on the other hand, will be born with hemophilia. Some women who carry the gene can have significant bleeding difficulties and pass the mutation on to their sons and daughters.

While hemophilia is more commonly found in families with a history of the disorder, it has also been reported in families without a history of the blood disorder. This unusual kind of hemophilia is known as acquired hemophilia, and it occurs when the body’s immune system targets clotting components within the body. Treatment for Haemophilia will be different for acquired kind.

Types of Hemophilia

Hemophilia generally always affects men, although in rare cases, a female can be affected as well. 

Inherited hemophilia is divided into two types:

Type A: It is the most frequent variety and is caused by a lack of factor VIII, a protein that aids in the formation of clots in the blood. Classic hemophilia is the name given to this kind.

Type B: A lack of factor IX causes type B hemophilia. Christmas sickness is another name for this variety.

Hemophilia is most commonly diagnosed at birth, although it can also be acquired later in life if the body produces antibodies that attack and destroy clotting components. This kind of hemophilia is, however, extremely uncommon. Acquired hemophilia, commonly known as autoimmune hemophilia or acquired hemophilia A, is a type of acquired hemophilia (AHA).

Treatment for Hemophilia is determined by the type of Haemophilia individual consisting.

What Are The Sign and Symptoms of Hemophilia?

Bleeding, either persistent external bleeding or bruising after little trauma or for no apparent reason is the most common symptom. The severity of the symptoms varies depending on whether the patient has a mild, moderate, or severe case of the disorder.

Hemophilia signs and symptoms differ based on the number of clotting factors. You may only bleed after surgery or trauma if your clotting factor level is mildly lowered. If you have a significant deficiency, you can bleed easily and for no apparent cause.

The following are signs and symptoms of spontaneous bleeding:

Excessive bleeding from cuts or wounds, especially after surgery or dental work, for no apparent reason

  1. There are numerous huge or deep bruises
  2. Unexpected Vaccination-related bleeding
  3. Your joints may be inflamed, swollen, or tight
  4. You will have blood in your urine or feces
  5. Nosebleeding without reason
  6. Unexplainable irritability in babies

For people with severe hemophilia, brain bleeding is a serious condition. It is possible that it will put your life in danger. If you see any of the following indicators of bleeding, seek medical attention right away:

  1. Behavioral changes
  2. Excessive snoozing
  3. A headache that refuses to go away
  4. Neck ache
  5. Double sight vision 
  6. Vomiting
  7. Seizures or convulsions

What Are The Causes of Hemophilia?

When a person bleeds, the body usually aggregates blood cells into a clot to stop the bleeding. Clotting factors are proteins in the blood that help platelets form clots by interacting with them. When a clotting factor is lacking or the levels of the clotting factor are low, hemophilia development takes place.

Only the X chromosome contains the genes that control the synthesis of factors 8 and 9. Mutations in the factor VIII or factor 9 genes on the X chromosome causes hemophilia.

Congenital Hemophilia

Hemophilia is frequently inherited, which means that a person is born with it (congenital). Low clotting factor type is used to classify congenital hemophilia and that is a major cause of hemophilia.

Hemophilia A is the most frequent kind, which is linked to a low level of factor 8. Hemophilia B, which is associated with a low level of factor 9, is the next most frequent form.

Acquired Hemophilia 

Hemophilia can develop in people who have no family history of the disease. Acquired hemophilia is the medical term for this condition.

Acquired hemophilia is a type of hemophilia that occurs when the immune system targets the blood’s clotting factor 8 or 9. It has a connection to:

  1. Pregnancy
  2. Pregnancy Autoimmune conditions
  3. Cancer
  4. Drug  Reactions
  5. Multiple Sclerosis

The presence of hemophilia in one’s family is the most significant risk factor. Hemophilia is far more common in men than it is in women.

How Diagnosis of Hemophilia is Done?

A blood test is used to diagnose hemophilia. A little sample of blood will be taken from your vein and the level of clotting factor present will be measured by your doctor.

After that, the sample is assessed to determine the degree of the factor deficiency and the condition.

The following are the several levels of Hemophilia A severity:

Mild: occurs when the level of a component is between 6% and 30%. (about 25 percent of all cases)

Moderate: When factor levels are between 1% and 5%  (about 15 percent of all cases)

Severe: When factor levels are fewer than 1%, it is considered severe (about 60 percent of all cases)

The following are the several levels of Hemophilia B severity:

Mild: occurs when the level of a factor is between 6% and 49%.

Moderate: When factor levels are between 1% and 5%, it is considered moderate.

Severe:  When factor levels are fewer than 1%, it is considered severe.

Haemophilia Treatment cost in India

Haemophilia treatment cost in India starts from 650 USD.

Procedure

Treatment for Hemophilia

Hemophilia Treatment varies depending on the type of hemophilia you have. Treatment’s major goal is to replenish clotting factors so that a person can form clots and stop bleeding.

In the treatment of hemophilia for both types, hematologists use the most up-to-date, time-tested Factor Replacement Therapy.

Hemophilia A Treatment

A lack of clotting Factor 8 in the blood causes this bleeding condition. Hematology doctors will inject a medicine called desmopressin, which is a clotting Factor 8 that can temporarily raise the concentration of Factor 8 in your blood.

Hemophilia B Treatment

This form of the bleeding problem is caused by the lack or malfunction of clotting Factor 9. Replacement therapy, which helps boost the level of Factor 9 in the blood, is the most effective treatment. Infusing clotting agents, on the other hand, helps protect blood clots and keeps them in place to stop bleeding. Depending on the degree of the bleeding, both may be used concurrently.

 Depending on the type of hemophilia you have, your doctor may prescribe the further following treatment:

  1. Concentrated or Fix Product: These injected drugs, also known as clotting factors, are used to treat types A and B, respectively. Synthetic or human plasma can be used to make the medicine. Doctors frequently prescribe them as part of a long-term therapy plan called prophylaxis.
  2. Aminocaproic Acid: This drug works to keep blood clots from dissolving. This medication may be prescribed by a doctor prior to dental or other surgery.
  3. Non-Factor Replacement Therapies: These drugs are a novel type of therapy that replicates clotting factors using synthetic proteins. The drug is injected into the skin by a doctor. Emicizumab and desmopressin acetate are two examples of this therapy.
  4. Physical Therapy: If your joints have been affected by hemophilia, you may need to go to physical therapy for rehabilitation.
  5. Pain Management: If you are experiencing pain as a result of your disease, your doctor may prescribe or recommend pain medication to help you manage it.
  6. New Therapy: New forms of therapy, such as gene therapies and the use of monoclonal antibodies, are being investigated by scientists.

Suggestion

It’s important to remember that patients with hemophilia should avoid aspirin and ibuprofen. Blood clotting may be hampered by certain medications.

To ensure that clotting factors created from donated blood are even safer, receive hepatitis A and B immunizing vaccinations.

Finally, to preserve excellent health, follow the advice given to persons who do not have hemophilia:

  • Exercise on a regular basis (swimming is particularly good).
  • Maintain a healthy weight by eating nutritious foods.
  • Maintain proper dental hygiene.
The Most Important Frequently Asked Questions

Q: What medications should be avoided with hemophilia?

A: In persons with hemophilia, doctors frequently prescribe acetaminophen, such as Tylenol, for pain treatment. Take no aspirin, ibuprofen (Advil or Motrin), Aleve, or other nonsteroidal anti-inflammatory drugs (NSAIDs), or medicines containing salicylate. These medications have the potential to induce bleeding.

Q: Is paracetamol safe in hemophilia?

A: The use of paracetamol with trimeperidine in hemophiliac patients (even if they have hepatitis C) within the first 24 hours following high-trauma procedures is both effective and safe. Hemophiliac sufferers’ pain is a serious issue.

Q: What is a normal factor 8 level?

A: The use of paracetamol with trimeperidine in hemophiliac patients (even if they have hepatitis C) within the first 24 hours following high-trauma procedures is both effective and safe. Hemophiliac sufferers’ pain is a serious issue.

Q: Does hemophilia affect platelets?

A: While hemophiliacs’ thrombin generation is substantially compromised, primary hemostasis, or platelet function, has long been assumed to be normal. However, several investigations have found that hemophilia patients had longer bleeding periods, implying that primary hemostasis is also impacted.

Q: What is a bleeding test?

A: The bleeding time test is used to determine how well blood clots in a person’s body. The time it takes for the arteries to contract and platelets in the blood to seal the hole is measured in this test.

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Medsurge India is one of the pioneers and the most reputable company in the field of medical tourism in India. India offers World Class Medical Facilities, comparable with any of the Western and European countries. India has state of the art Hospitals and the finest medical experts. With the most excellent infrastructure, the best possible Medical facilities, accompanied with the most competitive prices, you can get the treatment done in India at the lowest charges. The Availability of Ayurveda and Naturopathy in the purest form makes India the most sought after health destination.

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