Muscle loss and weakness are symptoms of spinal muscular atrophy (SMA). Standing, walking, controlling head motions, and, in certain situations, breathing and swallowing might be challenging for someone with SMA. SMA affects some people from birth, while others develop later in adulthood. Some types have an impact on life expectancy. According to research, SMA affects one out of every 8,000–10,000 persons in the world. SMA has no cure, although novel medications like nusinersen (Spinraza) and onasemnogene abeparvovec-xioi (Zolgensma) may help reduce the disease’s progression. Spinal Muscular Atrophy Treatment cost in India is quite affordable when compared to that of other…
Muscle loss and weakness are symptoms of spinal muscular atrophy (SMA). Standing, walking, controlling head motions, and, in certain situations, breathing and swallowing might be challenging for someone with SMA. SMA affects some people from birth, while others develop later in adulthood. Some types have an impact on life expectancy.
According to research, SMA affects one out of every 8,000–10,000 persons in the world.
SMA has no cure, although novel medications like nusinersen (Spinraza) and onasemnogene abeparvovec-xioi (Zolgensma) may help reduce the disease’s progression.
Spinal Muscular Atrophy Treatment cost in India is quite affordable when compared to that of other wealthy nations. The success is partly attributable to the sophisticated medical technology found in Indian hospitals as well as the skill of the surgeons. Aside from these advantages, another crucial factor for Spinal Muscular Atrophy Treatment in India is its appeal around the world is its inexpensive cost without compromising clinical standards.
What is Spinal Muscular Atrophy (SMA)
A genetic condition labeled spinal muscular atrophy (SMA) affects the skeletal muscles, peripheral nervous system, and brain.
The word spinal appears in the disease name because the majority of the nerve cells that govern muscles are found in the spinal cord. SMA is muscular because its primary effect is on muscles, which do not receive signals from these nerve cells. Atrophy is the medical term for getting smaller, which is what generally happens to muscles when they’re not stimulated by nerve cells.
SMA is a motor neuron disease that causes the loss of nerve cells called motor neurons in the spinal cord.
The most common form of SMA (chromosome 5 SMA, also known as SMN-related SMA) has a wide range of onset, symptoms, and progression rates. Types 1 through 4 of chromosome 5-related SMA, which is commonly autosomal recessive, are categorized to account for these variances.
The age at which SMA symptoms appear generally coincides with the severity of motor function impairment: The stronger the influence on motor function, the younger the onset age. Children who show symptoms at birth or early in childhood usually have the lowest degree of functioning (type 1). SMA that develops later in life and has a milder course (types 2 and 3, and type 4 in teenagers or adults) is associated with higher levels of motor function.
What Are the Symptoms of Spinal Muscular Atrophy
The symptoms of Spinal Muscular Atrophy differ based on the type. In general, patients with SMA lose muscle control, movement, and strength as the disease progresses. Muscle loss worsens as you become older. The muscles closest to the spine and neck are the most severely affected by the condition. Some SMA patients never walk, sit, or stand. Others’ capacity to perform these acts deteriorates over time.
What Causes Spinal Muscular Atrophy
SMA patients either lack a portion of the SMN1 gene or have an altered (mutated) gene. SMN protein is produced by a healthy SMN1 gene. This protein is required for motor neurons to survive and function properly.
Motor neurons atrophy and die in people with SMA because they do not produce enough SMN protein. As a result, the brain loses its ability to govern voluntary motions, particularly those involving the head, neck, arms, and legs.
SMN2 genes produce a tiny quantity of SMN protein in people as well. An SMN2 gene can be found in up to eight copies in a single person. Because the extra genes compensate for the missing SMN1 protein, having several copies of the SMN2 gene usually results in less severe SMA symptoms. Rare causes of spinal muscular atrophy encompass mutations in genes other than the SMN gene (non-chromosome 5).
How is Spinal Muscular Atrophy Diagnosed
When parents or caregivers observe symptoms of SMA in a child, they frequently seek medical help.
For spinal muscular atrophy treatment in India, a doctor will do a thorough medical examination, as well as a family history and a physical examination. They will examine the muscles for floppy or flaccidity, as well as deep tendon reflexes and tongue muscle twitching.
The following Spinal Muscular Atrophy tests may be used for diagnosis purposes:
- Blood Tests
- A muscle biopsy
- During pregnancy, genetic tests such as amniocentesis or chorionic villus sampling are performed.
- Electromyography (EMG)
EMG can be used to examine the health of muscles and the nerve cells that regulate them, known as motor neurons. The doctor can evaluate the fetus in the womb via amniocentesis or chorionic villus sample.
SMA genetic screening at birth is recommended in several jurisdictions. If the illness is detected early enough, it may be possible to cure it before symptoms arise.
What Is the Cost of Spinal Muscular Atrophy Treatment in India
Spinal Muscular Atrophy Treatment Cost in India has extremely reduced treatment expenses as compared to other nations. Additionally, the level of medical care and services offered there is on par with those of the greatest hospitals in the world. Even after excluding the fees of travel, housing, and food, the Spinal Muscular Atrophy Treatment cost in India starts from USD 4200. Additionally, the overall Spinal Muscular Atrophy Treatment Cost in India will depend on the sort of therapy you require and the results of your examination.
Spinal Muscular Atrophy Treatment Cost in India can vary depending on a number of criteria, such as
- The package of Spinal Muscular Atrophy Treatment in India can depend on the hospital’s preference.
- Doctor’s competence and experience in the subject.
- The patient’s situation: The patient’s disease and whether additional modalities are required for comprehensive treatment.
- Duration of hospitalization and stay for Spinal Muscular Atrophy Treatment in India.
- Need for post-operative care.
- Spinal Muscular Atrophy Treatment in India prices can depend on the type of hospital and rooms you stay.
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Why India is a Top Destination For Spinal Muscular Atrophy Treatment
India’s healthcare industry has advanced significantly over the past years, as seen by the notable accomplishments it has made. One of the industries that have contributed the most to revenue and is expanding quickly is healthcare. Both public and private providers support the healthcare industry.
Spinal Muscular Atrophy Treatment in India has improved a lot. Modern medical technology and highly skilled medical personnel are available in India. The World Health Organization (WHO) and the US Food and Drug Administration support medical facilities and services. In addition, India provides less expensive treatment alternatives than the US and the UK without sacrificing the standard of healthcare. About one-fourth, less is spent on therapy in India than it is in the United States.
India has an advantage over other countries in terms of medical tourism because of the following:
- The majority of the medical professionals working in Indian hospitals have received their training at medical centers in the US, Europe, or other affluent countries.
- The majority of medical professionals speak English well.
- Many hospitals in India have access to cutting-edge medical and diagnostic technology from large international enterprises.
- The best nurses in the world come from India. Nearly 10,000 nurses are graduated each year from India’s nearly 1000 accredited nurse training programs, the majority of which are affiliated with teaching hospitals.
- Even the most frugal traveler can afford premium services and opulent facilities.